diff --git a/runtime.js b/runtime.js
index 547b8c6af462faae1a859160a54fd1d107dd52c3..57030742671c525d1717a1fb11eea0c7ffd59689 100644
--- a/runtime.js
+++ b/runtime.js
@@ -86,9 +86,9 @@ var runtime = (function (exports) {
   // This is a polyfill for %IteratorPrototype% for environments that
   // don't natively support it.
   var IteratorPrototype = {};
-  IteratorPrototype[iteratorSymbol] = function () {
+  define(IteratorPrototype, iteratorSymbol, function () {
     return this;
-  };
+  });
 
   var getProto = Object.getPrototypeOf;
   var NativeIteratorPrototype = getProto && getProto(getProto(values([])));
@@ -102,8 +102,9 @@ var runtime = (function (exports) {
 
   var Gp = GeneratorFunctionPrototype.prototype =
     Generator.prototype = Object.create(IteratorPrototype);
-  GeneratorFunction.prototype = Gp.constructor = GeneratorFunctionPrototype;
-  GeneratorFunctionPrototype.constructor = GeneratorFunction;
+  GeneratorFunction.prototype = GeneratorFunctionPrototype;
+  define(Gp, "constructor", GeneratorFunctionPrototype);
+  define(GeneratorFunctionPrototype, "constructor", GeneratorFunction);
   GeneratorFunction.displayName = define(
     GeneratorFunctionPrototype,
     toStringTagSymbol,
@@ -217,9 +218,9 @@ var runtime = (function (exports) {
   }
 
   defineIteratorMethods(AsyncIterator.prototype);
-  AsyncIterator.prototype[asyncIteratorSymbol] = function () {
+  define(AsyncIterator.prototype, asyncIteratorSymbol, function () {
     return this;
-  };
+  });
   exports.AsyncIterator = AsyncIterator;
 
   // Note that simple async functions are implemented on top of
@@ -412,13 +413,13 @@ var runtime = (function (exports) {
   // iterator prototype chain incorrectly implement this, causing the Generator
   // object to not be returned from this call. This ensures that doesn't happen.
   // See https://github.com/facebook/regenerator/issues/274 for more details.
-  Gp[iteratorSymbol] = function() {
+  define(Gp, iteratorSymbol, function() {
     return this;
-  };
+  });
 
-  Gp.toString = function() {
+  define(Gp, 'toString', function() {
     return "[object Generator]";
-  };
+  });
 
   function pushTryEntry(locs) {
     var entry = { tryLoc: locs[0] };
@@ -733,7 +734,7 @@ var runtime = (function (exports) {
 ));
 
 try {
-  regeneratorRuntime = runtime;
+  globalThis.regeneratorRuntime = runtime;
 } catch (accidentalStrictMode) {
   // This module should not be running in strict mode, so the above
   // assignment should always work unless something is misconfigured. Just