diff --git a/ui/components/app/edit-gas-popover/edit-gas-popover.component.js b/ui/components/app/edit-gas-popover/edit-gas-popover.component.js
index 4e84ec5bf..7a862e42d 100644
--- a/ui/components/app/edit-gas-popover/edit-gas-popover.component.js
+++ b/ui/components/app/edit-gas-popover/edit-gas-popover.component.js
@@ -3,6 +3,7 @@ import PropTypes from 'prop-types';
 
 import { useDispatch, useSelector } from 'react-redux';
 import { useGasFeeInputs } from '../../../hooks/useGasFeeInputs';
+import { useShouldAnimateGasEstimations } from '../../../hooks/useShouldAnimateGasEstimations';
 
 import {
   GAS_ESTIMATE_TYPES,
@@ -27,6 +28,7 @@ import {
   hideSidebar,
   updateTransaction,
 } from '../../../store/actions';
+import LoadingHeartBeat from '../../ui/loading-heartbeat';
 
 export default function EditGasPopover({
   popoverTitle = '',
@@ -41,6 +43,8 @@ export default function EditGasPopover({
   const dispatch = useDispatch();
   const showSidebar = useSelector((state) => state.appState.sidebar.isOpen);
 
+  const shouldAnimate = useShouldAnimateGasEstimations();
+
   const showEducationButton =
     mode === EDIT_GAS_MODES.MODIFY_IN_PLACE && process.env.SHOW_EIP_1559_UI;
   const [showEducationContent, setShowEducationContent] = useState(false);
@@ -181,45 +185,48 @@ export default function EditGasPopover({
         )
       }
     >
-      <div style={{ padding: '0 20px 20px 20px' }}>
+      <div style={{ padding: '0 20px 20px 20px', position: 'relative' }}>
         {showEducationContent ? (
           <EditGasDisplayEducation />
         ) : (
-          <EditGasDisplay
-            showEducationButton={showEducationButton}
-            warning={warning}
-            showAdvancedForm={showAdvancedForm}
-            setShowAdvancedForm={setShowAdvancedForm}
-            dappSuggestedGasFeeAcknowledged={dappSuggestedGasFeeAcknowledged}
-            setDappSuggestedGasFeeAcknowledged={
-              setDappSuggestedGasFeeAcknowledged
-            }
-            maxPriorityFeePerGas={maxPriorityFeePerGas}
-            setMaxPriorityFeePerGas={setMaxPriorityFeePerGas}
-            maxPriorityFeePerGasFiat={maxPriorityFeePerGasFiat}
-            maxFeePerGas={maxFeePerGas}
-            setMaxFeePerGas={setMaxFeePerGas}
-            maxFeePerGasFiat={maxFeePerGasFiat}
-            estimatedMaximumNative={estimatedMaximumNative}
-            isGasEstimatesLoading={isGasEstimatesLoading}
-            gasFeeEstimates={gasFeeEstimates}
-            gasEstimateType={gasEstimateType}
-            gasPrice={gasPrice}
-            setGasPrice={setGasPrice}
-            gasLimit={gasLimit}
-            setGasLimit={setGasLimit}
-            estimateToUse={estimateToUse}
-            setEstimateToUse={setEstimateToUse}
-            estimatedMinimumFiat={estimatedMinimumFiat}
-            estimatedMaximumFiat={estimatedMaximumFiat}
-            hasGasErrors={hasGasErrors}
-            onEducationClick={() => setShowEducationContent(true)}
-            mode={mode}
-            transaction={transaction}
-            gasErrors={gasErrors}
-            onManualChange={onManualChange}
-            {...editGasDisplayProps}
-          />
+          <>
+            <LoadingHeartBeat active={shouldAnimate} />
+            <EditGasDisplay
+              showEducationButton={showEducationButton}
+              warning={warning}
+              showAdvancedForm={showAdvancedForm}
+              setShowAdvancedForm={setShowAdvancedForm}
+              dappSuggestedGasFeeAcknowledged={dappSuggestedGasFeeAcknowledged}
+              setDappSuggestedGasFeeAcknowledged={
+                setDappSuggestedGasFeeAcknowledged
+              }
+              maxPriorityFeePerGas={maxPriorityFeePerGas}
+              setMaxPriorityFeePerGas={setMaxPriorityFeePerGas}
+              maxPriorityFeePerGasFiat={maxPriorityFeePerGasFiat}
+              maxFeePerGas={maxFeePerGas}
+              setMaxFeePerGas={setMaxFeePerGas}
+              maxFeePerGasFiat={maxFeePerGasFiat}
+              estimatedMaximumNative={estimatedMaximumNative}
+              isGasEstimatesLoading={isGasEstimatesLoading}
+              gasFeeEstimates={gasFeeEstimates}
+              gasEstimateType={gasEstimateType}
+              gasPrice={gasPrice}
+              setGasPrice={setGasPrice}
+              gasLimit={gasLimit}
+              setGasLimit={setGasLimit}
+              estimateToUse={estimateToUse}
+              setEstimateToUse={setEstimateToUse}
+              estimatedMinimumFiat={estimatedMinimumFiat}
+              estimatedMaximumFiat={estimatedMaximumFiat}
+              onEducationClick={() => setShowEducationContent(true)}
+              mode={mode}
+              transaction={transaction}
+              hasGasErrors={hasGasErrors}
+              gasErrors={gasErrors}
+              onManualChange={onManualChange}
+              {...editGasDisplayProps}
+            />
+          </>
         )}
       </div>
     </Popover>
diff --git a/ui/components/app/transaction-detail/index.scss b/ui/components/app/transaction-detail/index.scss
index 538f469d8..d5e732d5e 100644
--- a/ui/components/app/transaction-detail/index.scss
+++ b/ui/components/app/transaction-detail/index.scss
@@ -1,4 +1,6 @@
 .transaction-detail {
+  position: relative;
+
   .transaction-detail-edit {
     text-align: end;
     padding-top: 20px;
diff --git a/ui/components/app/transaction-detail/transaction-detail.component.js b/ui/components/app/transaction-detail/transaction-detail.component.js
index aacb71b8c..63594be25 100644
--- a/ui/components/app/transaction-detail/transaction-detail.component.js
+++ b/ui/components/app/transaction-detail/transaction-detail.component.js
@@ -1,20 +1,19 @@
 import React, { useContext } from 'react';
 import PropTypes from 'prop-types';
-import classNames from 'classnames';
 
 import { I18nContext } from '../../../contexts/i18n';
+import { useShouldAnimateGasEstimations } from '../../../hooks/useShouldAnimateGasEstimations';
 
 import TransactionDetailItem from '../transaction-detail-item/transaction-detail-item.component';
+import LoadingHeartBeat from '../../ui/loading-heartbeat';
 
 export default function TransactionDetail({ rows = [], onEdit }) {
   const t = useContext(I18nContext);
+  const shouldAnimate = useShouldAnimateGasEstimations();
 
   return (
-    <div
-      className={classNames('transaction-detail', {
-        'transaction-detail--editable': Boolean(onEdit),
-      })}
-    >
+    <div className="transaction-detail">
+      <LoadingHeartBeat active={shouldAnimate} />
       {onEdit && (
         <div className="transaction-detail-edit">
           <button onClick={onEdit}>{t('edit')}</button>
diff --git a/ui/components/ui/loading-heartbeat/index.js b/ui/components/ui/loading-heartbeat/index.js
new file mode 100644
index 000000000..fae2e886d
--- /dev/null
+++ b/ui/components/ui/loading-heartbeat/index.js
@@ -0,0 +1,36 @@
+import classNames from 'classnames';
+import PropTypes from 'prop-types';
+import React, { useEffect, useRef } from 'react';
+
+export default function LoadingHeartBeat({ active }) {
+  const heartNode = useRef(null);
+
+  const LOADING_CLASS = 'loading-heartbeat--active';
+
+  // When the loading animation completes, remove the className to disappear again
+  useEffect(() => {
+    const eventName = 'animationend';
+    const node = heartNode?.current;
+    const eventHandler = () => {
+      node?.classList.remove(LOADING_CLASS);
+    };
+
+    node?.addEventListener(eventName, eventHandler);
+    return () => {
+      node?.removeEventListener(eventName, eventHandler);
+    };
+  }, [heartNode]);
+
+  return (
+    <div
+      className={classNames('loading-heartbeat', {
+        [LOADING_CLASS]: active,
+      })}
+      ref={heartNode}
+    ></div>
+  );
+}
+
+LoadingHeartBeat.propTypes = {
+  active: PropTypes.bool,
+};
diff --git a/ui/components/ui/loading-heartbeat/index.scss b/ui/components/ui/loading-heartbeat/index.scss
new file mode 100644
index 000000000..0b1b095f2
--- /dev/null
+++ b/ui/components/ui/loading-heartbeat/index.scss
@@ -0,0 +1,23 @@
+.loading-heartbeat {
+  position: absolute;
+  top: 0;
+  bottom: 0;
+  left: 0;
+  right: 0;
+  opacity: 0;
+  background: #fff;
+  display: none;
+
+  &--active {
+    display: block;
+    animation: heartbeat 2s ease-in-out;
+  }
+}
+
+@keyframes heartbeat {
+  0% { opacity: 0; }
+  25% { opacity: 1; }
+  50% { opacity: 0.5; }
+  75% { opacity: 1; }
+  100% { opacity: 0; }
+}
diff --git a/ui/components/ui/ui-components.scss b/ui/components/ui/ui-components.scss
index 0f95c6af8..f585f9052 100644
--- a/ui/components/ui/ui-components.scss
+++ b/ui/components/ui/ui-components.scss
@@ -31,6 +31,7 @@
 @import 'identicon/index';
 @import 'info-tooltip/index';
 @import 'list-item/index';
+@import 'loading-heartbeat/index';
 @import 'loading-indicator/loading-indicator';
 @import 'loading-screen/index';
 @import 'menu/menu';
diff --git a/ui/hooks/useShouldAnimateGasEstimations.js b/ui/hooks/useShouldAnimateGasEstimations.js
new file mode 100644
index 000000000..df588c0ec
--- /dev/null
+++ b/ui/hooks/useShouldAnimateGasEstimations.js
@@ -0,0 +1,28 @@
+import { useRef } from 'react';
+import { isEqual } from 'lodash';
+
+import { useGasFeeEstimates } from './useGasFeeEstimates';
+
+export function useShouldAnimateGasEstimations() {
+  const { isGasEstimatesLoading, gasFeeEstimates } = useGasFeeEstimates();
+
+  // Do the animation only when gas prices have changed...
+  const lastGasEstimates = useRef(gasFeeEstimates);
+  const gasEstimatesChanged = !isEqual(
+    lastGasEstimates.current,
+    gasFeeEstimates,
+  );
+
+  // ... and only if gas didn't just load
+  // Removing this line will cause the initial loading screen to stay empty
+  const gasJustLoaded = isEqual(lastGasEstimates.current, {});
+
+  if (gasEstimatesChanged) {
+    lastGasEstimates.current = gasFeeEstimates;
+  }
+
+  const showLoadingAnimation =
+    isGasEstimatesLoading || (gasEstimatesChanged && !gasJustLoaded);
+
+  return showLoadingAnimation;
+}