diff --git a/test/e2e/helpers.js b/test/e2e/helpers.js
index cd05e38e0..72a82acc8 100644
--- a/test/e2e/helpers.js
+++ b/test/e2e/helpers.js
@@ -9,6 +9,7 @@ const FixtureServer = require('./fixture-server');
 const PhishingWarningPageServer = require('./phishing-warning-page-server');
 const { buildWebDriver } = require('./webdriver');
 const { ensureXServerIsRunning } = require('./x-server');
+const GanacheSeeder = require('./seeder/ganache-seeder');
 
 const tinyDelayMs = 200;
 const regularDelayMs = tinyDelayMs * 2;
@@ -23,6 +24,7 @@ async function withFixtures(options, testSuite) {
     dapp,
     fixtures,
     ganacheOptions,
+    smartContract,
     driverOptions,
     dappOptions,
     title,
@@ -46,6 +48,14 @@ async function withFixtures(options, testSuite) {
   let failed = false;
   try {
     await ganacheServer.start(ganacheOptions);
+    let contractRegistry;
+
+    if (smartContract) {
+      const ganacheSeeder = new GanacheSeeder(true);
+      await ganacheSeeder.deploySmartContract(smartContract);
+      contractRegistry = ganacheSeeder.getContractRegistry();
+    }
+
     if (ganacheOptions?.concurrent) {
       const { port, chainId } = ganacheOptions.concurrent;
       secondaryGanacheServer = new Ganache();
@@ -100,6 +110,7 @@ async function withFixtures(options, testSuite) {
     await testSuite({
       driver,
       mockServer,
+      contractRegistry,
     });
 
     if (process.env.SELENIUM_BROWSER === 'chrome') {
diff --git a/test/e2e/seeder/ganache-contract-address-registry.js b/test/e2e/seeder/ganache-contract-address-registry.js
new file mode 100644
index 000000000..bfad708d3
--- /dev/null
+++ b/test/e2e/seeder/ganache-contract-address-registry.js
@@ -0,0 +1,28 @@
+/*
+ * Use this class to store pre-deployed smart contract addresses of the contracts deployed to
+ * a local blockchain instance ran by Ganache.
+ */
+class GanacheContractAddressRegistry {
+  #addresses = {};
+
+  /**
+   * Store new contract address in key:value pair.
+   *
+   * @param contractName
+   * @param contractAddress
+   */
+  storeNewContractAddress(contractName, contractAddress) {
+    this.#addresses[contractName] = contractAddress;
+  }
+
+  /**
+   * Get deployed contract address by its name (key).
+   *
+   * @param contractName
+   */
+  getContractAddress(contractName) {
+    return this.#addresses[contractName];
+  }
+}
+
+module.exports = GanacheContractAddressRegistry;
diff --git a/test/e2e/seeder/ganache-seeder.js b/test/e2e/seeder/ganache-seeder.js
new file mode 100644
index 000000000..85cc199bc
--- /dev/null
+++ b/test/e2e/seeder/ganache-seeder.js
@@ -0,0 +1,88 @@
+const { ethers } = require('ethers');
+const ganache = require('ganache');
+const { contractConfiguration } = require('./smart-contracts');
+const GanacheContractAddressRegistry = require('./ganache-contract-address-registry');
+
+/*
+ * Ganache seeder is used to seed initial smart contract or set initial blockchain state.
+ */
+class GanacheSeeder {
+  constructor(debug = false) {
+    this.debug = debug;
+    this.smartContractRegistry = new GanacheContractAddressRegistry();
+  }
+
+  /**
+   * Deploy initial smart contracts that can be used later within the e2e tests.
+   *
+   * @param contractName
+   */
+
+  async deploySmartContract(contractName) {
+    if (this.debug) {
+      console.log('Deploying smart contracts using GanacheSeeder');
+    }
+
+    const ethersProvider = new ethers.providers.Web3Provider(
+      ganache.provider(),
+      'any',
+    );
+    const contractFactory = new ethers.ContractFactory(
+      contractConfiguration[contractName].abi,
+      contractConfiguration[contractName].bytecode,
+      ethersProvider.getSigner(),
+    );
+
+    let contract;
+
+    if (contractName === 'hst') {
+      contract = await contractFactory.deploy(
+        contractConfiguration.hst.initialAmount,
+        contractConfiguration.hst.tokenName,
+        contractConfiguration.hst.decimalUnits,
+        contractConfiguration.hst.tokenSymbol,
+      );
+    } else {
+      contract = await contractFactory.deploy();
+    }
+
+    await contract.deployTransaction.wait();
+
+    if (this.debug) {
+      console.log(
+        `Contract mined! address: ${contract.address} transactionHash: ${contract.deployTransaction.hash}`,
+      );
+    }
+    this.storeSmartContractAddress(contractName, contract.address);
+  }
+
+  /**
+   * Store deployed smart contract address within the environment variables
+   * to make it available everywhere.
+   *
+   * @param contractName
+   * @param contractAddress
+   */
+  storeSmartContractAddress(contractName, contractAddress) {
+    if (this.debug) {
+      console.log(
+        `Storing smart contract address: [${contractName}] => ${contractAddress}`,
+      );
+    }
+    this.smartContractRegistry.storeNewContractAddress(
+      contractName,
+      contractAddress,
+    );
+  }
+
+  /**
+   * Return an instance of the currently used smart contract registry.
+   *
+   * @returns GanacheContractAddressRegistry
+   */
+  getContractRegistry() {
+    return this.smartContractRegistry;
+  }
+}
+
+module.exports = GanacheSeeder;
diff --git a/test/e2e/seeder/smart-contracts.js b/test/e2e/seeder/smart-contracts.js
new file mode 100644
index 000000000..c2394bb9a
--- /dev/null
+++ b/test/e2e/seeder/smart-contracts.js
@@ -0,0 +1,43 @@
+const {
+  hstBytecode,
+  hstAbi,
+  piggybankBytecode,
+  piggybankAbi,
+  collectiblesAbi,
+  collectiblesBytecode,
+  failingContractAbi,
+  failingContractBytecode,
+} = require('../../../node_modules/@metamask/test-dapp/dist/constants.json');
+
+const hstFactory = {
+  initialAmount: 100,
+  tokenName: 'TST',
+  decimalUnits: 4,
+  tokenSymbol: 'TST',
+  bytecode: hstBytecode,
+  abi: hstAbi,
+};
+
+const collectiblesFactory = {
+  bytecode: collectiblesBytecode,
+  abi: collectiblesAbi,
+};
+
+const piggybankFactory = {
+  bytecode: piggybankBytecode,
+  abi: piggybankAbi,
+};
+
+const failingContract = {
+  bytecode: failingContractBytecode,
+  abi: failingContractAbi,
+};
+
+const contractConfiguration = {
+  hst: hstFactory,
+  collectibles: collectiblesFactory,
+  piggybank: piggybankFactory,
+  failing: failingContract,
+};
+
+module.exports = { contractConfiguration };