diff --git a/app/scripts/controllers/transactions/tx-state-manager.js b/app/scripts/controllers/transactions/tx-state-manager.js
index 879aac56c..d59b5a058 100644
--- a/app/scripts/controllers/transactions/tx-state-manager.js
+++ b/app/scripts/controllers/transactions/tx-state-manager.js
@@ -249,9 +249,9 @@ export default class TransactionStateManager extends EventEmitter {
     const txsToDelete = transactions
       .reverse()
       .filter((tx) => {
-        const { nonce } = tx.txParams;
+        const { nonce, from } = tx.txParams;
         const { chainId, metamaskNetworkId, status } = tx;
-        const key = `${nonce}-${chainId ?? metamaskNetworkId}`;
+        const key = `${nonce}-${chainId ?? metamaskNetworkId}-${from}`;
         if (nonceNetworkSet.has(key)) {
           return false;
         } else if (